【摘要】 本文应用单克隆抗体技术,检测了30例心血管疾病病人的外周血B细胞、T细胞及其亚群。实验结果表明,原发性高血压和冠心病患者外周血B细胞数均比正常人高（P<0.05）;OKT₃⁺细胞百分率比正常低（P<0.01）;OKT₈⁺细胞数有下降趋势;OKT₄⁺细胞数百分率与正常人相同;其中原发性高血压患者的T₄/T₈比值较正常人高（P<0.01）而冠心病患者的T₄/T₈比值较正常人略有提高但无显著性差异（P<0.05）。实验结果提示:心血管疾病的发生与机体免疫功能紊乱有一定关系。更多还原

【Abstract】 The peripheral blood B and T lymphocyte subsets of 30 patients with primary hypertension and coronary heart disease were determined by utilizing McAbs. The results show that the B cell value in 30 Patients and the ratio of T4/T8 in Patients with primary hypertension are sigmificantly higher than that of normal people; the number of OKT3+ cell in 30 Patients are remarkablely lower than that of nomal people. The value of OKT4+ cell and OKT8+ cell in patients are not found to be significantly varied compared with normal,but the percentage of OKT8+ cell in primary hypertension patients is slightly lowered. The results indicate that the immunologic disorders in patients have some influences on coronary heart disease and hypertension.更多还原