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血浆置换术治疗异基因骨髓移植后纯红细胞再生障碍性贫血(附1例报告)

Treatment of Pure Red Cell Aplasia Post Allogeneic Bone Marrow Transplantation with Plasmapheresis

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【作者】 张义成宋善俊邹萍胡俊斌李珺

【Author】 Zhang Yicheng; Song Shanjun; Zou Ping; et al(Institute of Hematology, Tongji Medical University, Wuhan)

【机构】 同济医科大学血液病研究所

【摘要】 本文报告1例重症再生障碍性贫血患者因接受ABO血型不合供体的异基因骨髓移植后并发纯红细胞再生障碍性贫血。采用血浆置换术2次,共置换出患者体内血浆3.2L后,血清抗"A"血型抗体滴度由1∶64下降至1∶8,骨髓幼红细胞比分逐渐上升,由血浆置换术前的0.005上升至术后12周的0.21;红细胞输注量逐渐减少,血红蛋白逐渐升高,患者目前已完全恢复正常2年余。

【Abstract】 A patient with severe aplastic anemia received ABO incompatible allogeneic bone marrow transplantation; After transplantation, the patient complicated with pure red cell aplasia. We treated the patient with plasmapheresis and exchanged 3.2 liters of plasma, The anti "A" isoagglutinin titre decreased from 1: 64 to 1: 8 postpheresis; The percentage of bone marrow erythroblast increased from 0.005 to 0.21; the RBC requirement was greatly declined and the hemoglobin has became normal for 2 years.

  • 【文献出处】 临床血液学杂志 ,JOURNAL OF CLINICAL HEMOTOLOGY , 编辑部邮箱 ,1995年02期
  • 【分类号】R556
  • 【下载频次】40
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