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急性非淋巴细胞白血病16号染色体畸变及其异常细胞形态学观察

Investigation on the Aberrations of Chromosome 16 Associated with an Abnormal Cytomorphology in Acute Nonlymphocytic Leukemia

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【作者】 丘镜滢洪波吴萍娜党辉单福香王德炳

【Author】 Qiu Jingying;Hong Bo;Wu Pingna;et al(Institute of Hematology,Beijing Medical University)

【机构】 北京医科大学血液病研究所

【摘要】 报告近两年来我室从68例急性非淋巴细胞白血病(ANLL)中检出的7例具有inv16(P13q12,de1(16q22)和t(16;16)的染色体畸变。对具有该畸变者的异常骨髓细胞形态进行了观察,并讨论了该畸变在ANLL诊断和鉴别诊断中的意义。

【Abstract】 The karyotypes of 68 cases with ANLL were analysed in our laboratory from 1991 to 1993 at the time of diagnosis,The abnormalities of chromosome 16 including inv 16(P13 q22),del(16q22),and t(16;16)(p13 q22 were found in 7 of 68 cases.At the same time,their abnormal marrow cyto morphology was observed.The clinical singnificance of the aberrations of chromosome 16 associated eith specific cyto morphologic feature in ANLL was discussed.

  • 【文献出处】 临床血液学杂志 ,JOURNAL OF CLINICAL HEMOTOLOGY , 编辑部邮箱 ,1995年01期
  • 【分类号】R733.710.2
  • 【下载频次】47
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