【摘要】 本实验对７４例急性脑梗塞患者和４６例正常人的血清过氧化脂质（ＬＰＯ）、水溶性荧光物质（ＷＳＦＳ）、谷胱甘肽过氧化物酶（ＧＰＸ）和维生素Ｅ（ＶＥ）水平进行了测定，结果显示：脑梗塞患者的ＬＰＯ和ＷＳＦＳ均明显高于正常人（均Ｐ＜０．０１），ＧＰＸ和ＶＥ均明显低于正常人（Ｐ＜０．０１，＜０．０５）。脑梗塞患者ＬＰＯ增高与ＷＳＦＳ增高呈显著正相关，且二者与ＧＰＸ、ＶＥ的降低均呈显著负相关，表明脑梗塞患者体内自由基产生增加，脂质过氧化作用增强。建议在本病的早期，应给予适当的抗氧化治疗。更多还原

【Abstract】 AbstractSerum lipid peroxides(LPO),water一solved fluorescence substance(WSFS),glutathioneperoxidase(GPX)and vitamin E(VE ) were med,sured in 7 4 patients with acute cerebral infarc-tion and 46 controls. It was showed that the levels of LPO and WSFS in the patients were signifi-cantly higer than that in the controls(P<0.01),but GPX and VE lower(P<0.01,<0.05),The increase of LPO in the patients had obviously positive correlation to that of WSFS.Both LPOand WSFS had negative correlation to GPX and VE respectively.The results indicated that thefree radical increases and lipid peroxidation enhances in the patients with acute cerebral infarc-tion,We suggest that in the early stage of the disease proper antiperoxidatton treatment shoule begiven.更多还原