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TOPV 强化免疫效果的研究

Study on intensive immunity effect of TOPV

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【摘要】 实验证明,100名完成 TOPV 基础免疫的18—24月龄儿童一轮强化免疫1个月后检测,3型血清抗脊髓灰质炎病毒中和抗体分别为1:45.95、1:124.08和1:34.14;两轮强化免疫1个月后检测,除 I—SPVAb(1:57.70)比一轮强化略有增加(P<0.01)外,其余两型抗体未见增加(P>0.05)。据此认为,TOPV 基础免疫接种率水平较高,无病例或罕有病例的地区,只要能做好防止漏服的充分准备,采用“扫荡式”一轮强化免疫方法,可以获得与两轮强化免疫同样地控制 Polio 发病的满意效果。

【Abstract】 Our experiments showed that in 100 TOPV foundamentally immuned children at the ages of 18—24 months one month after one round of intensive immunity,type Ⅲ serum antipoliomyelitis virus and antibody were 1:45.95,1:124.08 and 1:34.14,respectively.One month after two rounds of intensive immunity,the other two types of antibody showed no increase(P>0.05), except that I—SPVAb(1:57:70)increased a little more than the first round of intensifying(P >0.01).There fore we believe that because the rate of TOPV foundamental immunity is high,in the areas with no case or rare cases,as long as we are well prepared to avoid missing medication the same satisfactory effect as that of two rounds of intense immunity can be obtained in the con- trol of the attack of polio by the “MOP—UP” method of one round intense immunity.

【关键词】 免疫; 脊髓灰质炎; 儿童;
【Key words】 immunity; poliomyelitis;
  • 【分类号】R186
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