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电刺激黑质网状部抑制大鼠丘脑腹内侧核神经元的自发放电

THE SPONTANEOUS FIRINGS OF VM NEURONS WERE INHIBITED BY SNR STIMULATION IN THE RAT

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【作者】 高东明; 肖爱珍; 倪忠阁; 岳春良; 常志洁; 李鹰; 李子军; 黄荣芝;

【Author】 Gao Dongming; Xiao Aizhen; Ni Zhongge (Department of Electrophysiological research)Yue Chuenliang; Chang Zhijie; Li Ying; Li Zijun (Department of Physiology)

【机构】 锦州市和平医院;

【摘要】 本文用细胞外单位记录方法观察了电刺激大鼠黑质网状部(SNR)对丘脑腹内侧核(VM)神经元放电活动的影响。结果显示电刺激SNR抑制大多数VM神经元的自发放电;反应分为单纯抑制和先抑制后兴奋两种不同形式。结果提示。在大鼠,SNR-VM传入投射主要通过抑制VM神经元的放电活动,参与对躯体运动的调节。

【Abstract】 The effect of electrical stimulation of substantia nigra,pars reticulata(SNR).on the ventromedial thalamic nucleus(VM)was investigated using extracellular-recording method in rats.The stimulation of SNR inhibited the majority of spontaneous firings in VM neurons.This inhibition was divided into two types:inhibitory type and inhibitoryexcitatory type. This result suggests that the SNR-VM afferent projection could be involved in the regulation of the body movement by inhibiting the spontaneous activities of VM neurons

  • 【文献出处】 锦州医学院学报 ,JOURNAL OF JINZHOU MEDICAL COLLEGE , 编辑部邮箱 ,1995年04期
  • 【分类号】R338.1
  • 【下载频次】30
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