【摘要】 采用聚乙二醇(PEG)为相转移催化剂,无水氟化钾代替醋酸钾对苯甲醛与乙酐的Perkin反应合成肉桂酸工艺进行了改进,降低了反应温度,缩短了反应时间,最佳反应条件为苯甲醛:乙酐:氟化钾=1:3:1,PEG2%(mol),反应时间1.5h,反应温度160℃,所得肉桂酸的产率高达84.2%.更多还原

【Abstract】 Perkin synthesis of cinnamic acid from acetic anhydride and benzaldehyde was improved by using. Polyethylene glycol(PEG) as phase transfer catalyst and using anhydrous potassium fluoride instead of potas-sium acetate. Higher yield(84. 2%),lower reaction temperature and shorter time were obtained. Optimum conditions were benzaldehyde : acetic anhydride : potassium fluoride = 1 : 3 : 1(molar ratio),reaction tempe-rature 160℃ ,reaction time 1. 5h and PEG 2% mol.更多还原