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贾第虫研究──Ⅰ.西蒙氏贾第虫(Giardia simoni)滋养体和包囊对实验动物的感染

STUDIES ON GIARDIA SPP.I.EXPERIMENTAL INIFECTION OF LABORATORY ANIMALS WITH TROPHOZOITES AND CYSTS OF GIARDIA SIMONI

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【作者】 高诚符杰金玫蕾鲍世民

【Author】 Gao Cheng;Fu Jie;Jin Meilei;Bao Shimin(Shanghai Laboratory Animals Centre,Academia Sinica,Shanghai 200233)

【机构】 中国科学院上海实验动物中心

【摘要】 作者从自然感染西蒙氏贾第虫(Giardiasimoni)的金黄地鼠肠道内和粪便中分离、收集滋养体和包囊,分别经口感染大鼠、小鼠、豚鼠和兔子。结果表明兔子和脉鼠均不感染,大鼠、小鼠均不同程度地感染该虫,且4周龄大鼠比8周龄大鼠更易感(P<0.05),而在小鼠中成年鼠与老年鼠对西蒙氏贾第虫的敏感性没有差异(P>0.05)。滋养体在感染动物的肠道内主要分布于十二指肠前段,中前段和中段。同时观察到结肠和直肠内有包囊,这表明该虫在大鼠、小鼠体内完成了其生活史。作者还对感染前后的滋养体作了蛋白银和铁苏木精染色比较,二者在形态上完全相同。

【Abstract】 A number of rats,mice, guinea pigs and rabbits were orally given trophozoites and cysts of Giardia simoni collected from naturally infected hamsters.The results showed that guinea pigs and rabbits resisted the infection of G.simoni,but rats and mice were infected.Young rats were more susceptible than adult rats to trophozoites and cysts.The trophozoites mainly distributed in anterior, mid-anterior and mid-part of the duodenum of the infected rats and mice.The cysts were found in the large intestine of the infected animals,indicating that G.simoni has completed its life cycle in rats and mice.The trophozoites from hamsters,rats and mice were morphologically compared after being stained with silver protein(protargol)and hematozylin.Observations showed that trophozoites were all identical in morphology.

【关键词】 西蒙氏贾第虫滋养体包囊动物感染
【Key words】 Giardia simoniTrophozoiteCystExperimentalInfection
【基金】 中国科学院上海分院及中科院上海实验动物中心资助
  • 【文献出处】 寄生虫与医学昆虫学报 ,ACTA PARASITOLOGICA ET MEDICA ENTOMOLOGICA SINICA , 编辑部邮箱 ,1995年02期
  • 【分类号】R382.21
  • 【被引频次】1
  • 【下载频次】49
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