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大鼠心肌及动脉壁雄激素受体的探讨

A STUDY ON ANDROGEN RFCEPTORS IN CARDIAC MUSCLE AND ARTERIAL WALL OF RAT

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【作者】 常笑雪; 王淑钗; 王耀华;

【Author】 Chang Xiaoxue. Wang Shucai, Wang Yaohua (Department of Histology and Embryology. Luoyang Medical School, Luoyang 471003)

【机构】 洛阳医学高等专科学校组织胚胎学教研室; 洛阳医学高等专科学校组织胚胎学教研室 洛阳471003; 洛阳471003; 洛阳471003;

【摘要】 采用免疫组化ABC间接法对30例大鼠的心脏及动脉进行了雄激素受体的检测.结果显示:心肌雄激素受体阳性例数为73%(22/30);主动脉阳性例数为64%(16/25);股动脉阳性例数为92%(22/24);心肌中冠状动脉及其分支和前列腺组织中小动脉均为阳性.结果表明:在大鼠心肌和动脉壁存在着雄性激素受体,提示雄激素可能对心血管系统起调节作用.

【Abstract】 Androgen receptors in the cardiac muscle and the arterial walls of 30 adult rats were studiedby ABC immunohistochemical staining indirect method. The results showed that the positive caserate of androgen receptors was 73%(22/30) in the cardiac muscle, 60% (16/25) in the aortic wallsand 92% (22/24) in the walls of the femoral artery. Androgen receptors in the co ronary artery ofthe cardiac muscle and in the small artery of the prostate were also positive. The result indicatesthat there are androgen receptors in the cardiac muscle and arteries. This suggests that androgenhas a regulation function on the cardiovascular system.

【关键词】 雄激素受体; 心肌; 动脉; 大鼠;
【Key words】 androgen receptor; myocardium; artery; rat;
  • 【文献出处】 解剖学杂志 ,Chinese Journal of Anatomy , 编辑部邮箱 ,1995年06期
  • 【分类号】R329
  • 【被引频次】15
  • 【下载频次】39
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