【摘要】 <正> 自然流产的原因很多,如生殖器官异常、内分泌紊乱、免疫因素、感染疾病和遗传因素等。其中染色体异常是引起自然流产的重要原因之一。我室自1980年5月至1993年6月,对在遗传咨询门诊中涉及自然流产及分娩畸胎史的患者作了细胞遗传学检查,对有染色体异常患者进行家系调查和监测,以期再孕时进行产前诊断和提供优生指导。 资料和方法 检查对象为遗传咨询门诊病人,凡有一次或一次以上自然流产、分娩畸胎史或流产合并有畸胎史更多还原

【Abstract】 (10. 5%) sex chromosome abnormality. In the balanced translocation. 11 cases (64. 7%) showed reciprocal balanced translocation, and 6 cases (35. 3%) showed Robertsonian translocation. This paper suggested that patients of homologous Robertsonian translocation should be sterilized,and as for the nonhomologous patients, amniotic cells from amniocentesis at the second trimester of pregnancy should be cultured to make the prenatal diagnosis.G-banded chromosome complements were analysed from 285 cases who had once or more spontaneous abortions and malformed fetus. Nineteen cases of this study showed chromosomal abnormalities ( 6. 7 %), among which 17 cases (89. 5%) showed balanced translocation and 2 cases更多还原