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~153Sm-EDTMP对骨转移癌疼痛的止痛效果

 ̄153Sm-EDTMP for Moderate and severe Bone Cancer Pain

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【作者】 邓侯富罗顺忠谭天秩莫廷树梁正路蒲满飞礁健钟尚炎王全林胡赢州刘中林

【Author】 Deng Houfu; Luo Shunzhong;Tan Tianzhi;Mo Tingshu;Liang Zhenglu;Pu Manfei; Jiao Jian; Zhong Shangyang; Wang Quanlin; Hu Yingzhou; Liu Zhonglin(1).Department of Nuclear Medicine; (2).Institute of Southwest Nuclear Physics and

【机构】 西南核物理与化学研究所

【摘要】 作者用 ̄153Sm-EDTMP治疗了136例骨癌疼痛病人,用药后疼痛完全缓解者49例(36.0%),中度缓解者77例(56.6%),总止痛有效率为92.6%。结果表明:76例中、重度骨癌疼痛患者的年龄、性别、剂量对止痛效果无明显影响(P>0.05),但以胸部(肋骨)疼痛为主的骨癌患者,其疼痛缓解的时间最早出现,与其它各组比较有显著性差异(P<0.05)。

【Abstract】 One hundred and thirt-six patientswith bone cancer pain were treated with  ̄153Sm- EDTMP (ethylenediamine-tetramethylene phosphonicacid).Pain free was noted in 49 cases(36%, 49/136)and pain relief in 77 cases(56.6%,77/136),the totalrelief rate being 92.6%(126/136). The data from 76patients with moderate and severe pain showed therewere no significant relationshps between the patients′age,the dose of  ̄153Sm-EDTMP and the analgesic ef-fects(P> 0. 05).The pain relief observed in the pa-tients with chest pain ( ribs metastases)was earlierthan that in other groups(P<0. 05 ). We didn′t findany clinical side-effects,so  ̄153Sm-EDTMP is safe for use.

【关键词】  ̄153钐乙二胺四甲撑膦酸骨癌止痛
【Key words】 ?53Sm-EDTMPBonecancerAnalgesiceffect
【基金】 国家自然科学基金
  • 【文献出处】 华西医科大学学报 ,JOURNAL OF WEST CHINA UNIVERSITY OF MEDICAL SCIENCES , 编辑部邮箱 ,1995年04期
  • 【分类号】R738.1
  • 【被引频次】18
  • 【下载频次】38
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