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消毒剂二氧化氯的毒性效应研究

Study on the toxicity of chlorine dioxide

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【作者】 吕文戈吕风臣程学敏巴月李晨燕

【Author】 Lu Wenge,Lu Fengchen,Cheng Xuemin,Ba Yue,Li Chenyan (Department of Environmental Health, Henan Medical University, Zhengzhou 450052 Zhengzhou Epidemic Prevention Station,Zhengzhou 450053)

【机构】 河南医科大学环境卫生学教研室!郑州450052郑州市卫生防疫站!郑州450053

【摘要】 按照消毒技术规范操作程序,对二氧化氯的刺激性.一般毒性和致突变作用进行了试验 观察。结果显示:该消毒剂的最大应用浓度对眼粘膜有一定的刺激性,毒性分级属中等毒性,但在体 内蓄积性极低并可产生耐受性,致突变试验结果也为阴性反应。提示该消毒剂的正常使用是安全 的。

【Abstract】 CIO2 is one kind of disinfectant extensively used in environmental health disinfection.Its toxicity was studied in animal experiments. It was found that its oral LD50 in mice was 134. 90 mg/kg (95% confidence limits was 113.76-159. 96 mg/kg). Skin irritation test with 0.1- 0.5% showed no local irritative reactions. Eye irritation test indicated that 0. 5% had some irritatitive effect on conjunctiva. Both micronucleus and sperm tests in mice were negative. On the basis of the experimental results it is considered that the disinfectant is safe to use in disinfection practice.

【关键词】 二氧化氯消毒剂毒性效应致突变作用
【Key words】 CIO2disinfectanttoxicological effect
  • 【文献出处】 河南医科大学学报 ,Journa of Henan Medical University , 编辑部邮箱 ,1995年04期
  • 【分类号】R994.6
  • 【被引频次】9
  • 【下载频次】102
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