【摘要】 采用内压式和外压式中空纤维膜组件超滤红霉素发酵滤液，用麦夸脱（Ｍａｒｑｕａｒｄｔ）算法对浓差极化－凝胶层模型和Ｆｌｅｍｍｅｒ复合模型（以下简称复合模型）进行参数拟合与检验，比较了两个模型的优劣。结果表明，由于复合模型既考虑了浓差极化的影响，也考虑了超滤膜中尚未形成凝胶层部分压力对通量的影响，使其与实验结果吻合得比凝胶层模型好，可用于通量预测，具有较高的精确性和较广的适应性。更多还原

【Abstract】 The composite model and concentration polarizationgel layer model were com-pared,Their parameters were obtained on the basis of the experimental data of ultrafiltratingerythromycin fermentation broth filtrate,using both the innerand outer-pressured hollow-fiber equipment.The results showed that the composite model was more advantageous andcoincided with the experimental data better by taking account of the entire membrane sur-hce,including the portion before the formation of the gel layer.更多还原