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广西肝癌高发区儿童HBsAg自然阴转随访研究

A FOLLOW-UP STUDY ON SPONTANEOUS DISA-PPEARANCE OF HBsAG IN CHILOREN IN HIGH LIVER CANCER INCJDENCE AREAS IN GUANGXI

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【作者】 黄天壬张振权何振芳莫林华徐庆芬黄昭东梁任祥

【Author】 Huang Tianren;Zhang Zhenquan;He Zhenfang;et al

【机构】 广西肿瘤研究所

【摘要】 对广西肝癌高发区6~12岁儿童无症状HBsAg携带者485例追踪随访一年,观察其自然阴转。结果自然阴转率为249%,而75.1%的研究对象依然保持其HBsAg携带状态。其中男性自然阴转率(20.9%)显著低于女性(30.3%)(p<0.05)。合并HBeAg阳性者,HBsAg自然阴转率(19.6%)又显著低于HBeAg阴性者(32.5%)(P<0.01)。结果提示,在广西肝癌高发区男性HBsAg携带率较高。

【Abstract】 A follow-up study for a peroid of one year was performed in a high primaryLiver Cancer(PLC)area in Guangxi to investigate the spontaneous disappearance of HBsAg in485 6~12 years old children,The results showed that the rate ofspontaneous disappearance ofHBsAg(RSD)of HBsAg in these children was only 24.9%,and that 75.1% of the children stilldisplayed HBsAg in their serum after a peroid of one year.The RSD of HBsAg of the boys(20.9%)was significantly lower thanthat of the girls(30.3%).Besides. RSD of HBsAg ofHBsAg carriers withHBeAg in their serum was significantly lower than those withoutHBeAg.The result suggeted that the rate of HBsAg carrier was usually higher in men than inwomen.

【关键词】 HBsAg携带者肝癌儿童阴转
【Key words】 HBsAg carrierprimary liver cancerchildrenspontaeous disappearance
  • 【文献出处】 广西医科大学学报 ,ACTA ACADEMIAE MEDICINAE GUANGXI , 编辑部邮箱 ,1995年03期
  • 【分类号】R735.7
  • 【下载频次】32
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