【摘要】 应用低硒大骨节病区粮、病区粮加硒和非病区粮饲料喂养大鼠。测定大鼠血清以及心、肝组织中的超氧化物歧化酶（ＳＯＤ）的活性和肝组织中脂质过氧化物（ＴＢＡ）含量，观察低硒大骨节病区粮对大鼠体内脂质代谢的影响。结果表明，病区粮组肝组织ＴＢＡ较病区粮加硒组与非病区粮组显著升高，病区粮加硒组与非病区粮组肝ＴＢＡ含量无显著性差异。ＳＯＤ活性变化不明显。这些说明大鼠体内脂质代谢紊乱似与低硒有关，加硒可改善这种代谢。更多还原

【Abstract】 SD rats were fed with Se-deficient diet from a Kashin-Beck disease endemic area, Se-deficient diet supplemented with sodium selenite and Se-sufficient from non-KBD endemic area. Results showed that the liver TBA contents were increased significantly in Se-deficient group, compared with the other two groups: and that SOD activities of serum, heart and liver existed little difference among the three groups. Those indicated that the increment of liipid peroxide in the Se-deficient rats seem to be caused by the selenium deficiency and Se-supplementsed to the Se-deficient diet may ameliorate the impairment of lipid metabolism to some extent.更多还原