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α-芳甲酰基烯酮二硫缩醛的新合成方法
A New Method for the Synthesis of α-Aroyl Ketene Dithioacetals
【摘要】 以碳酸钾为碱,芳甲酰丙酮(1)与二硫化碳、卤代烃反应得到2-乙酰基-2-芳甲酰基烯酮硫代缩醛(2),2在乙硫醇钾作用下脱乙酰基生成标题化合物(3)。1→3的转化具有反应条件温和、产物产率高及对3中各种缩醛基均可通用等特点。
【Abstract】 A facile approach to the synthesis of the title compounds 3 are reported in this paper.Assisted by potassium ethylthioate,2-acetyl-2-aroyl ketene dithioacetals 2(prepared easily from aroylacetones 1)were deacetylated to afford the title compounds 3.The reaction conditions from 1 to 3 were very mild and the yields were high.
【关键词】 α-芳甲酰基烯酮二硫缩醛;
合成;
乙硫醇钾;
去乙酰基;
【Key words】 ?Aroyl ketene dithioacetals; Synthesis; Potassium ethylthioate; Deacetylation;
【Key words】 ?Aroyl ketene dithioacetals; Synthesis; Potassium ethylthioate; Deacetylation;
【基金】 国家教育委员会优秀青年教师基金
- 【文献出处】 高等学校化学学报 ,CHEMICAL RESEARCH IN CHINESE UNIVERSITIES , 编辑部邮箱 ,1995年12期
- 【分类号】O623.541
- 【被引频次】11
- 【下载频次】159