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中药药性多因素量化分析初探──毒性的相关因素

Quantitative Analysis With Multifactor for Chinese Herbal Medicine:Relevent Factors of Toxicity

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【作者】 陈晓亮归筱铭

【Author】 Chen Xiaoliang;Gui Xiaoming(Fujian Institute of TCM & Pharmacology)

【机构】 福建省中医药研究院

【摘要】 本研究对全国通用的3906种中药的性味、归经、炮制、科属、药用部位、化学成分、药理作用等7项与药性有关的因素,共4万余条原始资料,应用微机检索进行中药毒性相关因素分析。数据表明3906种中药中大毒药<1%;药性属热性的中药具有不同程度的毒性占59.6%;中药毒性还与其科属如毛艮科、大戟科、天南星科等,以及化学成分如生物硷等密切相关。结果提示使用热性中药应于慎重。

【Abstract】 More than 40,000 original data about the propertises of 3906 kinds of common used Chinese herbal medicines in seven aspects such as the nature and tast,channel tropism,drugs processing,family classfication,chemical composisition,medicinal part and pharmacological effects were computerized and the relevent factors of toxicity were analysed.The result showed that 1 % of these 3906 drugs were strong toxic.59.7% of the drugs with hot nature had the toxicity in verying degrees,and the toxicity was closely related to their family classfication and chemical composition. It is suggested that it should be with great care to apply the drugs with hot nature to clinical practice.

  • 【文献出处】 福建中医学院学报 ,JOURNAL OF FUJIAN COLLEGE OF TRADITIONAL CHINESE MEDICINE , 编辑部邮箱 ,1995年01期
  • 【分类号】R285.1
  • 【被引频次】25
  • 【下载频次】294
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