【摘要】 本文对尚未补碘的碘缺乏病区人群进行了口服碘油丸前后甲状腺功能和自身抗体的研究。结果表明补碘前,甲状腺功能处于代偿状态,放射性碘摄取呈典型的碘饥饿改变,甲状腺自身抗体水平正常,未检出抗体阳性者;而补碘后,碘饥饿状态显著改善,病情明显好转,但甲状腺功能仍旧代偿,甲状腺自身抗体水平明显增高,抗体阳性者显著增多。提示服碘油虽可纠正机体缺碘状态、改善甲状腺功能状态,却易使成年人机体产生甲状腺自身抗体,而造成甲状腺自身免疫功能紊乱。更多还原

【Abstract】 Thyroid functions and thyroid autoantibodies of the inhabitants in a nonsupplied iodine deficient area were studied before and after administering oral iodized oil capsule. The results showed that thyroid functions were in state of compensation, radioiodine uptake values increased, levels of thyroid autoantibodies were normal,and that positive autoantibodies were not detected before. But after iodine supplementation,the state in iodine deficiency was improved markedly,the goiter prevalence and morbidity greatly decreased,however,thyroid functions were still in state of compensation,levels of thyroid autoantibodies increased significantly,and the patients with positive autoantibodies were more than before. It suggested that human iodine nutrition and thyroid functions were improved dramatically, yet thyroid autoantibodies produced and thyroid autoimmune might disorder.更多还原