【摘要】 本文对甘肃３个基本控制病点和３个相对较重病点，进行气象环境、居住状况、饮水和粮食卫生学质量、经济收入及硒营养等项目流行病学对比调查，以探讨导致大骨节病下降的可能因素。结果表明，粮食卫生学质量和饮水质量的改善、部分地区居民居住状况改变、经济收入增加和硒水平提高与病情下降有一定关系。但任何单一因素都难以成为导致病情下降的唯一原因，而是诸因素共同作用的综合效应。为此，提倡和坚持以补硒为主的综合措施是当前防治大骨节病的较佳选择。更多还原

【Abstract】 In order to explore epidemic decline of Kaschin一Beck disease in Gansu,some relative factors,such as meteorological environment,housing conditions,hygienic quality of drinking water and food,economic income and selenium nutrition,were investigated by way of epidemiological comparison at three prelimianrilycontrolled endemic spots and relatively serious endemic spots respectively. The results showed that factors in-cluding improvement of housing conditions,increase in income and rise in selenium level could be related toepidemic decrease of the disease. However,not any single factor but the comprehensive effect of several fac-tors resulted in the decline. Therefore,the comprehensive measures of taking selenium supplementation as thekey should be encouraged and maintained in controlling Kaschin一Beck disease at present.更多还原