【摘要】 发现人红白血病细胞株ＴＦ－１可在人重组白细胞介素－９（ＩＬ－９）刺激下长期生长达５个月，ＩＬＬ－９可抑制ＴＦ－１细胞的ＤＮＡ片段化，抗ＧＭ－ＣＳＦ抗体可抑制ＩＬ－９刺激的ＴＦ－１细胞增殖，从而提供了ＩＬ－９的一个新生物学效应。更多还原

【Abstract】 we found a human erythroleukemia cell line TF-1 could be stimulated by recombinant human interleukin-9 (IL-9)to long term proliferation up to 5 months, and cellular DNA fragrnentation was inhibited.The antibody a-gainst human granulocyte-macrophage colony stimulating factor(GM-CSF)inhibited the effect of IL-9. This studysuggests that IL-9may induce an autocrine loop of growth in the TF-1 cells. The results here provide a new bio-logical effect of IL-9.更多还原