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X射线照射小鼠体内自由基及过氧化脂质含量的变化
Changes of free radicals and LPO in mice irradiated by X-ray
【摘要】 本文用电子自旋共振(ESR)方法测定了X射线照射后小鼠脾脏自由基含量及用硫代巴比妥酸法测定了肝脏过氧化脂质(LPO)的变化。结果表明,在照射后1、3Gy,自由基含量升高,分别为对照组的1.21和2,62倍,3Gy照射后,随时间延长自由基含时亦逐渐增加。而LPO在不同剂量照射后随剂量的增加而增加。3Gy照射后至48h,LPO逐渐升高,至72h开始下降。其变化与自由基的变化基本一致。
【Abstract】 Free radical in X-irrdited mice was studied by ESR technique and LPO content wasalso investigated at same time. The results showed that free radicals in spleen gradually increased in 1and 3 Gy irradiated groups compared with normal.After 3 Gy irradiation,free radicals in spleenwere enhanced with time. While,LPO content in liver increased with different doses and it fluctuatedat different times after 3 Gy irradiation.
- 【文献出处】 白求恩医科大学学报 ,JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE , 编辑部邮箱 ,1995年03期
- 【分类号】R818.023
- 【被引频次】1
- 【下载频次】37