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山羊羔淋巴集结的研究

STUDY ON THE PEYER’S PATCHES OF GOAT LAMB

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【作者】 张红卫丛英姿于士广

【Author】 ZHANG HONG-WEI CONG YING-ZI YU SHI-GUANG (Department of Biology, Shandong University, Jinan 250100)

【机构】 山东大学生物学系!济南250100

【摘要】 对不同发育时期山羊羔淋巴集结(Peyer’s patches)、简称 PP的显微和亚显微结构的观察显示羊PP的发生和组织学特征与鸟类法氏囊极为相似。同时,羊羔PP提取液可提高仔兔和仔鸡血清抗体的滴度,促进淋巴组织的发育。实验结果表明山羊PP是B淋巴细胞发生的重要部位,山羊PP中含有类似法氏囊素的物质。

【Abstract】 The experimental results revealed that the development and morphological characteristics of kid’s Peyer’s patches (PP) were similar to that of bursa of Fabricius. The PP of new born kid already possessed typical lymphoid structures, which developed during the embryonic stage, instead of the stimulation of the foreign antigens. Ileum Peyer’s patches (IPP) o f the new born kid appeared with the same histological features as the bursa fo Fabricius. After birth, both T and B lymphocytes were already presented in Jejunum Peyer’s patches (JPP) where B lymphocytes further differentiated into plasma cells. Ipp and JPP became well developed during growth of kid, and they may also perform the function of peripheral lymphoid organs. The present experiments also revealed that the extracts of kid’s PP could promote the immunity of young rabbits and chicken by increasing the production of antibodies and enhancing the development of the B lymphocytes areas of the lymphoid tissue. The extracts of kid’s PP are quite similar to the bursal extracts. It may contain the bursin-like subtances. The result indicates that the PP of kid may be considered as one of the equivalents of bursa of Fabricius.

【基金】 发育免疫学课题研究的一部分,由高校博士点专项基金资助,基金批文号93C11
  • 【文献出处】 动物学报 ,Acta Zoologica Sinica , 编辑部邮箱 ,1995年02期
  • 【分类号】S852.4
  • 【被引频次】5
  • 【下载频次】61
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