【摘要】 应用免疫组织化学技术对１１４例胃癌进行雌激素受体（ＥＲ）检测。结果表明，１１４例胃癌中ＥＲ阳性２７例，阳性率为２３．７％，其中女性ＥＲ阳性率（３３．９％）明显高于男性（１３．８％），差异有显著性（Ｐ＜０．０５）。临床Ⅲ，Ⅳ期胃癌、肉眼ＢｏｒｒｍａｎｎⅣ型胃癌、组织学弥漫型胃癌及伴淋巴结转移的胃癌ＥＲ阳性率明显增高，其差异有显著性（Ｐ＜０．０５）。提示胃癌ＥＲ表达与其生物学行为有一定关系。更多还原

【Abstract】 Paraffin-embedded materials from 114 patients with primary gastric cancer were examined for the expression of the extrogen receptor(ER) with the avidin-biontin complex method.A significant positive correlation was found between the ER status and lymph node status,ER positive cases were characterized grossly as Borrmann lV Ⅳ,TNM Ⅲ,Ⅳ and microscopically as diffuse type with scirrhous growth pattern.The positive rate of ER in the female was higher than that in the male(P<0.05).These results indicate that ER detected by the ABC method may be used as biomarker for tumor differentiation.更多还原