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硒化卡拉胶的致突变作用研究

STUDY ON THE MUTAGENESIS OF KAPPA-SATENCAR- RAGGEENAN(K-Se)

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【作者】 王慧敏吴翠娥胡蓉芳顾素斐朱士雅王小玲曹群立

【Author】 Wang Huimin,Wu cuie,Hu Rongfang,Gu Sufei, Zhu Shiya,Wang Xiaoling,Cao Qunli School lf Public Health,Shanghai Medical University, Shanghai 200032

【机构】 上海医科大学公共卫生学院

【摘要】 本文通过沙门氏菌致突变试验(Ames试验),小鼠骨髓嗜多染红细胞微核试验及小鼠精子致畸形试验的检测,探讨K-Se有无致突变潜在毒性。结果未测到K-Se对体细胞及生殖细胞的潜在致突变作用。提示K-Se在致突变作用方面是安全的。关键词

【Abstract】 This paper reported the results of mutagenesis of K-Se assayed with theSalmonella mutagenicity test (Ames test);micronucleus test of polychromatic erythroblast inmouse bone marrow and aberration of sperm test in mouse. The results showed that the mu-tagenesis to somatic cells and reproductive cells has not been detected under the condition ofthese tests.It is believed that K-Se maybe safe on potential mutagenesis.

  • 【文献出处】 癌变.畸变.突变 ,CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS , 编辑部邮箱 ,1995年02期
  • 【分类号】R994.4
  • 【被引频次】5
  • 【下载频次】74
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