节点文献
家兔实验性动脉粥样硬化不同实验方法的比较
Comparative Studies on Different Method Making Experimental Atherosclerosis in Rabbit
【摘要】 对24只家兔应用乳化胆固醇灌注法和自食胆固醇法,进行实验性家兔动脉粥样硬化对比性研究。系统地观察两组实验家兔在3个月实验周期内高脂血症和主动脉粥样硬化病灶的变化,试图对乳化胆固醇灌注法和自食胆固醇法进行比较。结果表明:灌注法能控制实验家兔每日摄取胆固醇的剂量,使血脂骤升并保持在高水平,所制造实验性家兔动脉粥样硬化准确度高,病变程度严重,实验阳性率高。以上各项均优于自食胆固醇法。
【Abstract】 Atherosclerosis was investigated by perfusing emulsified cholesteral and feeding cholesteral on 24 rabbits. Systemically changes of hyperlipoidemia and aortic atherosclerosis were observed in two experimental groups during experimental period at three nonths. The authors made the comparative studies on experimental method between perfuing emulsified cholesteral and feeding cholesteral. The results showed that controlling daily dose of cholesteral, increasing content of lipid in blood and remaining high level of lipid in blood were made by using perfusing method. The atherosclerosis made by using Perfusing methods had severe pathologic changes. The successing rate of this method was high, Its locating rate was high. It was better than feeding method.
【Key words】 Emulsified cholesteral perfusion; Hyperlipoidemia; Atherosclerosis; Methodlogic comparision;
- 【文献出处】 临床实用神经疾病杂志 , 编辑部邮箱 ,1994年04期
- 【分类号】R543.5
- 【下载频次】30