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大鼠实验性脾虚证胃电波和胃运动波的研究

Study on Gastroelectric Activity and Gastric Motility in Experimental Spleen Deficiency Rats

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【作者】 曲瑞瑶曲柏林曾文红王秀琴曾晓蓓杨进李玲凤徐杰

【Author】 Qu Rui-yao;Wang Xiu-qin;Yang Jin;et al(Capital College of Medicine,Beijing 100054)

【机构】 首都医学院

【摘要】 采用银球三电极和高灵敏度应变片传感器分别记录胃电波和胃运动波。与正常对照组比较,实验性脾虚动物胃电慢波节律无明显改变,慢波振幅显著减小,快波振幅也减小,胃运动明显减弱。自然恢复组胃电波振幅和胃运动波仅有轻度恢复,经四君子汤加味治疗后的大鼠胃电波和胃运动波恢复接近正常对照水平。表明实验性脾虚证动物的胃电波和胃运动波有明显变化,四君子汤加味能够明显改善实验性脾虚证动物的胃电波和胃运动波。

【Abstract】 Using electrode and highly sensitive strain sensor to record alterations of gastroelectric activity and gastric motility,during experimental Spleen Deficiency(SD) rats was conducted.As compared with control,frequency of slow wave(time/3 min)did not obviously change(11.71±0.7l and 12.50±0.55,P<0.05),but amplitute(mV)of which reduced significantly to(14 ±0.05 and 0.37±0.04,P<0.01),while that of fast wave also decreased.In self-recovered group,the amplitute of slow wave recovered slightly (0.22±0.08 and 0.37±0.04,P>0.005).After treatment with modified Sijunzi Tang(四君子汤),the gastric activities of SD rats elevated to levels of control(P>0.05),but gastric motility remained weak in SD group.Although the motility of self-recovered group improved to a certain degree,however,the main indices had no significant difference from SD group(P>0.05).It suggested that there were significant changes of gastric activity in SD and Chinese herbs could improve the syndrome apparently.

  • 【文献出处】 中国中西医结合杂志 ,CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE , 编辑部邮箱 ,1994年03期
  • 【分类号】R256.3
  • 【被引频次】95
  • 【下载频次】147
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