【摘要】 作者以前瞻性分组治疗对照的方法,观察了丹参、心痛定、消心痛对100例慢性稳定型心绞痛伴无症状心肌缺血发作患者的临床疗效。其中丹参组32例,心痛定组36例,消心痛组32例。结果表明三种药物对缓解冠心病无症状心肌缺血发作都有肯定的作用(P<0.01)。但效应并非一致,以动态心电图不伴有任何症状的 ST 段水平下移≥0.1mV 发作的次数及其累积持续时间为判断指标,计算其1周缓解率和2周缓解率,心痛定组1周缓解率优于其它两组,而2周缓解率则以丹参组为著。说明丹参治疗冠心痛无症状心肌缺血疗效稳定可靠且无副作用,可推荐为首选药物。更多还原

【Abstract】 One hundred silent myocardial ischemic patients were studied in coronary heart disease(CHD).The patients were randomly allocated either to Salvia miltiorrhiza(SM).nifedipine or isosorbide dinitrate group for two weeks.They were given a dynamic electrocardiogram(DCG)detection at 1st weekend and 2nd weekend,and calculating time of ≥0.1 mV ST segment depression attack (∑ST↓ times)and accumulating time of it(∑ST↓ min)in the DCG.The result obtained confirmed that any group could effectively reduce the onset of silent myocardial ischemia in CHD(P<0.01).However.the clinical improvement rate of ∑ST↓ times and ∑ST↓ min in the DCG.nifedipine group was better than that of SM group and isosorbide dinitrate group in the 1st week.but in the 2nd week.the change in SM group was more significant than that of nifedipine group and isosorbide dinitrate group.更多还原