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复方黄芪对荷瘤小鼠血浆环核苷酸的影响

Effect of Huang Qi Compound on Cyclic Nucleotidesin plasma of The Tumor-bearing Mice

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【作者】 钟济秀朱玲玲李唯佳张红

【Author】 Zhong Jixiu. Zhu Lingling. Li Weigia, Zhang Hong

【机构】 浙江省中医药研究院

【摘要】 复方黄芪由黄芪、三七、萸肉和甘草组成,可降低荷瘤小鼠血浆cGMP含量,增加cAMP/cGMP比值。经正交试验方差分析,三七为降低血浆cGMP含量的主要药物,其余三药对荷瘤鼠血浆环核苷酸水平的影响不大。

【Abstract】 AbstractHuang Qi compound which consists of Huang Qi(Astragnlus mongholicus Bge). Sanqi (Panax pseudo-ginsengVar. notoginseng). Shan Zhugu (Cornus officinalis) and Gancao (Glycyrrhiza urulensis Fisch) could reduce cGMPlevel and raise cAMP/cGMP in plasma of the tumor-bearing mice. Variance analysis of the orthogonal design suggestedthat Sanqi was responsible for a decrease inc GMP and an increase in cAMP/cGMP in plasma. The effect of the other3 herbs on Cyclic Nucleotides in plasma was not significant.

【关键词】 黄芪三七环核苷酸
  • 【文献出处】 中药药理与临床 ,PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA , 编辑部邮箱 ,1994年04期
  • 【分类号】R285
  • 【被引频次】3
  • 【下载频次】43
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