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木香顺气冲剂对消化功能影响的实验研究
The Experimental Study on Influence of SaussureaLappa Clarke Compound Granulae on the Digestive Function
【摘要】 木香顺气冲剂15、7.5、3.75g/kg灌胃给药促进炭末在小鼠肠道的推进速度,十二指肠给药加强豚鼠在体回肠的收缩幅度,增加大鼠胃液分泌量,提高胃液中总酸及游离酸含量。豚鼠离体回肠实验,浓度1:500,1:1000,1:2000可见先收缩后松弛,收缩幅度加强,收缩频率减少。上述作用与吗丁啉相似。原剂型木香顺气丸的上述作用均不明显。
【Abstract】 AbstractOral administration of Saussurea Lappa Clarke Compound Granulae (SLCCG) in the doses of 15g. kg-1. 7. 5g kg-1 and3. 75g’ kg-1can move forward the propelling speed of carbon powder in the mice intestine. When giventhrough duodenum. SLCCG can strengthen the contractile range of guinea pig ileum in vivo. increase the secretion ofrat gastric juice and raise the content of the total acid and free arid in gastric juice. At the concentration of 1: 500.1: 1000 and 1 : 2000. SLCCG can increase the contractile range and decrease the contractile frequency. and causethe subsequent relaxation of guinea pig ileum in vitro. The results are similar to that of the positive control domperidontablet, and have no difference with the action of the original form of Saussurea Lappa Clarke compound pill. The results indicate that Saussurea Lappa Clarke compound Granulae have the advantage of increasing therapeutic action andconvanience.
- 【文献出处】 中药药理与临床 ,PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA , 编辑部邮箱 ,1994年04期
- 【分类号】R285
- 【被引频次】7
- 【下载频次】125