【摘要】 ３０例实体瘤，其中２８例为肺癌。化疗期并用呕必停（Ｎｏｖａｂａｎ）可预防高剂量化疗所致的呕吐。抗呕吐率（ＣＲ＋ＰＲ）因化疗（ＣＴ）方案而异：ＣＢＰ＋ＶＰ１６为１００％；ＣＴＸ为主者为８７．５％；高剂量ＣＤＤＰ为主者则为７８．６％。控制呕吐的关键在ＣＴ的ｄ１～ｄ３，特别是ＣＤＤＰ组。故呕必停为一有效控制由ＣＴ所致的呕吐药物，无严重副反应。更多还原

【Abstract】 Emesis in 30 patients with solid cancer,of them 28 were Lung cancer,caused by high doses of chemotherapy (CT)can be prevented by concomitant use of Novaban. The total antiemesis rate (CR+PR)varies with the variance of CT regimen. The results obtained were as following:CT regimen(CR+PR)% CBP+VP16 100 CTX 87.5 CDDP 78.6 Thekey point for control of emesis was on the first day to the third day of CT,especially in CDDP group. Novaban is an effective drug for prevention of vomiting in-duced by CT with no severe toxicity.更多还原