【摘要】 对３４例进食障碍（ＥＤ）患者及２１名健康人进行血ＤＳＴ及尿ＭＨＰＧ．ＳＯ４排出量的测定。结果表明ＥＤ患者血ＤｓＴ阳性率明显高于对照组。两组间尿ＭＨＰＧ．ＳＯ４的排出量未见明显差异。本文结果未发现ＥＤ患者ＨＰＡ轴脱抑制率与抑郁症状有关，但在抗抑郁治疗后，ＥＤ患者的ＤＳＴ阳性率下降，临床症状得到缓解。本研究结果表明，ＥＤ患者的ＨＰＡ轴功能异常极突出，并提示这种异常可能与异常的进食态度及行为关系密切。更多还原

【Abstract】 Dexamethasone suppresson test(DST) was performed and urinary MHPG. SO4 wasdetermined in 34 eating disorder(ED)patients without endogenous depression and 21 healthy volun-teers.The rate of escaping from DST in ED patients was significantly higher than that in controls.Though abnormal rate of DST in ED patients decreased after antidepressant therapy,no correlationwas found between abnormal rate of DST and severity of depressive symptoms.The results of presentstudy confirmed the dysfunction of hypothalomus-pituitary-adrenal axis in ED patients ,indicating thatthis may contributed to the abnormal eating attitude and behavior pattern in ED patients.更多还原