【摘要】 在用桃仁提取物、虫草菌丝治疗肝炎后肝硬化患者三个月获得疗效的基础上,本文对其中6例作了治疗前后肝脏病理学和免疫组化检查.发现治后患者肝脏硬度和色泽多有好转,肠系膜等处血管曲张度减轻,(?)状韧带水肿消失,腹水消退;多数病例肝细胞变性减轻,纤维间隔减少,半数以上病例肝窦周围和肝细胞之间Ⅰ、Ⅲ型胶原、PⅢNP以及FN减少。结果提示,桃仁提取物合虫草菌丝在阻断肝脏纤维组织增生方面有积极意义,因而在肝炎后肝硬化的治疗中具有一定的价值。更多还原

【Abstract】 On the basis of gaining effect of treating patients with posthepatitic cirrhosis with Ex-tractum Semen Persicae (ESP) plus Cordyceps Sinensis (Berk) Sace (CS) for 3 months. 6 of patients accepted laparoscopy and biopsy before and after the treatment. By the examinations of hepatic pathology and immunohistochemistry,it was found that,in most of the patients, the hardness degree and color of liver had been improved, the varicosity was lowered in mesentery and other parts,the resolution of dropsy in broad hepatic ligment and ascites was obvious. The degree of degeneration of hepatocytes was relieved and the fibrius septa had been reduced in most of the cases. Collagen type Ⅰ, Ⅲ,N-terminal propeptide of procolla-gen type Ⅲand fibronectin were decreased in paresinusoids and interhepatocytes in more than a half of patients. The results indicated that ESP plus CS had proper value in treatment of posthepatitic cirrhosis by inhibiting hyperplasia of fibrous in liver.更多还原