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流行性出血热病毒Z20株引起的细胞融合及其形态特点
Cell Fusion Induced by Strain Z20 of Epidemic Hemorrhagic Fever Virus and Its Morphologic Characteristics
【摘要】 实验结果表明:流行性出血热(EHF)病毒Z20株,在37℃经pH6.0细胞融合液处理,可引起细胞融合现象。随感染EHF病毒的细胞培养天数延长,细胞融合灶逐渐增多。细胞融合的形态特点表现为:首先细胞之间趋向紧密,伴有细胞膜消失,接着核大量聚集,进而变形,最后出现收缩形成融合灶。
【Abstract】 Epidemic hemorrbagic fever virus.strain Z20 caused cell fusion after exposing to acid environment(pH6. 0). As the infected cells(Vero-E6 cell line) were cultured longer. number of cell fusion foci increased. Morphologicall cell fusion showed that infected cells adhere each other, with disappearance of cell membrance and cluster of nuclei;the muclei became multiform and giant in feature;and finally a complete fusion foci estableshed.
【基金】 上海市卫生局资助
- 【文献出处】 中国公共卫生学报 , 编辑部邮箱 ,1994年03期
- 【分类号】R181.3
- 【被引频次】5
- 【下载频次】31