【摘要】 本文测试了孔隙率为１４％，孔径小于２μｍ的纯羟基磷灰石（ＨＡ）与兔胫骨皮质骨之间界面的抗张强度，２周时为０．７２ＭＰａ：４、８、１６周之间强度无明显差异平均为１．５ＭＰａ。扫描电镜观察表明，２周时拉伸断裂位于ＨＡ－骨界面，４周以后多在ＨＡ晶体颗粒之间。ＨＡ与骨生物适应性好，矿化组织可以直接沉着于ＨＡ表面或ＨＡ内部，近界面处的ＨＡ发生了一定的生物降解反应，且骨矿化与ＨＡ的降解可能达到某种平衡。更多还原

【Abstract】 Tensile strength of interface between hydroxyapatite(HA)and bone was tested. The porosity of HA was 14%,pore size less than 2μm.Two weeks after implantation into rabbit tibiae,tensile strength of the interface was 0.72 MPa,while the strength was not statistically in different between those of 4th, 8th and 16th weeks, the average strength being 1.5MPa.SEM showed,tensile failure occurred at the HA-hone interface 2weeks later,and 4 weeks later,the failure occurred among HA crystal particles instead of at the HA-bone interface.Calcified tissue may directly deposit on the HA surface or in the HA micropores.Nearby the interface biodegradation occurred at sintered necks of HA particles.The degradation of HA and calcification of bone may reach a certain balance.更多还原