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骨转移癌的153Sm-EDTMP止痛效果研究
Palliation of Bone Pain from Mctastatic Carcinoma with Samarium-153-EDTMP
【摘要】 采用153Sm—EDTMP治疗76例骨转移癌疼痛患者(男57例,女19例;年龄56~82岁)。首次或疗程内用药后疼痛完全缓解27例(35.5%,27/76),部分缓解43例(56.5%,43/76),总有效率为92%。影响因素研究表明:76例病人中,年龄、性别、剂量等对止痛效果无明显影响(P>0.05)。153Sm—EDTMP对全身各部位的骨转移癌疼痛均有良好的止痛效果,该药对减少临床麻醉剂用量,提高病人生存质量,延长病人寿命均有临床推广和应用价值。
【Abstract】 Seventy-six patients were treated with single doses of 153Sm-EDTMP for palliation of bone pain from metastatic carcinoma with 92% palliation. No significant differences ( P >0. 05) were found among various age groups,gender and dosage. Responses varied, large lesions responded poorly, small lesions with metastasis and axial skeleton lesions generally responded well.
【关键词】 153Sm-EDTMP;
骨转移癌;
缓解疼痛;
【Key words】 Skeletal Metastatic Carcinoma Palliation of Bone Pain 153Sm-EDTMP;
【Key words】 Skeletal Metastatic Carcinoma Palliation of Bone Pain 153Sm-EDTMP;
- 【文献出处】 中国老年学杂志 ,Chinese Journal of Gerontology , 编辑部邮箱 ,1994年04期
- 【分类号】R738.1
- 【被引频次】2
- 【下载频次】14