节点文献
大剂量顺铂联合环磷酰胺、平阳霉素治疗食管癌22例
HIgh dose cisplatin combination chemotherapy for advanced esophageal cancer
【摘要】 我们采用大剂量顺铂联合化疗治疗晚期食管癌22例。化疗方案为PCP(DDP+CTX+PYM)。顺铂剂量为100mg/m ̄2,一次给药,同时水化、利尿。本组病的完全缓解3例,部分缓解7例,总有效率(CR+PR)46%、中位缓解期5个月。化疗的毒副作用有骨髓抑制、消化道反应、脱发、发烧,而肝肾心神经系统毒性反应较轻。
【Abstract】 Twenty-two patients with advanced esophageal cancer were treated by hing close cisplatin(DDP)combination chemotherapy.The regimen was Pcp(DDP+CTX+PYM). DDP was given at adose of 100my/m ̄2 intravenously every 4 weeks. Three patients achieved CR.Seven cases PR. Theresponse rate (CR+PR) was46%. The side effects observed in these patients were as follow:myelosuppression.nausea and vomiting and alopecia and fever. Whereas the side-effects onkidney. liver heart,lung and neurologial system were very few.
【关键词】 大剂量顺铂;
联合化疗;
晚期食管癌;
【Key words】 High dose cisplatin; Combination chemotherapy; Advanced esophageal;
【Key words】 High dose cisplatin; Combination chemotherapy; Advanced esophageal;
- 【文献出处】 肿瘤防治研究 ,CANCER RESEARCH ON PREVENTION AND TREATMENT , 编辑部邮箱 ,1994年03期
- 【分类号】R735.105
- 【被引频次】9
- 【下载频次】26