【摘要】 应用１５３Ｓｍ─ＥＤＴＭＰ（ｅｔｈｙｌｅｎｅｄｉａｍｉｎｅｔｅｔｒａｍｅｔｈｙｌｅｎｔｐｈｏｓｐｈｏｎｉｃａｃｉｄ），治疗各种骨继发性肿瘤　　４０例。静脉一次给予量为２９．６ＭＢｑ／ｋｇ（０．８ｍＣｉ／ｋｇ），其中７例接受重复治疗。随访时间为３０天～１０个月。给药前２周内９９ｍＴｃ─ＭＤＰ与给药后１５３Ｓｍ─ＥＤＴＭＰ全身骨显象观察比较。该药副作用轻微，止痛效果显著。本组显效９例，有效２４例，总有效率为８２．５％，骨痛得到控制，生活质量明显提高。更多还原

【Abstract】 Abstract Sm-153-EDTMP(ethylenediaminetetramethylene phosphonic acid ),a beta-particle andγ-emitting radionuclide,was used for pain control of bonemetastasis.Fourty patients with bone metastasis were adiminstrated a single intravenous injection of 29.6 MBq/kg (0.8mCi/kg),and 7 of them received more than one injection.No obvious side effect was observed.The skeletal images obtained with Sm-153-EDTMP were similar to that of Tc-99m-MDP SPECT images.Follow up study (at least 30 days )revealed bone pain relief and improved quality of life in 82.5% of the treated patients.更多还原