【摘要】 应用山莨菪碱改善全身和患肢微循环、局部清创换药及控制糖尿病等综合治疗措施治疗糖尿病肢端坏疽３５１例，治愈３０１例（８５．７％），好转２７例（７．７％）、无效７例（２．０％）、截肢６例（１．７％）、死亡１０例（２．９％）。在治疗过程中患者的甲皱微循环明显改善。患肢血管多普勒检查见局部血管内径增宽、血流量增加。作者对糖尿病肢端坏疽的诊断与分型提出了初步标准。更多还原

【Abstract】 nisodamine was used to improve general circu-lation and the microcireulation of affected limbs.Measures like local debridement, dressing change, andcontrol of diabetes were applied in 35l patients withdiabetic limb gangrene. Of the 351 patients, 301(85.7 % ) were cured, 27(7.7% ) were improved, 7(2.0% )failed, 6(l.7%) had limb amputated, and 10(2.9%)died. In the treatment, the nail-fold microcireulationwas markedly improved. Doppler scan showed in-creased width and bloodflow of the vessels of theaffacted limbs. The criteria for the classification anddiagnosis of diabetes limb gangrene are suggested.更多还原