【摘要】 本实验测定了３４例慢性肾衰（ＣＲＦ）、２７例肾病综合征（ＮＳ）患者和１００例正常人血清脂质、脂蛋白（Ｌｐ）和载脂蛋白（Ａｐｏ）的含量，并观察了血透（ＨＤ）和非透析（ＮＤ）患者血清脂质、Ｌｐ、Ａｐｏ的浓度变化。结果显示：（１）与正常组比较，ＮＳ和ＣＲＦ患者血清脂质、Ｌｐ及Ａｐｏ的绝大多数指标有明显异常（Ｐ＜０．０１或０．０２或０．００１）；（２）比较ＨＤ和ＮＤ组，ＮＤ对ＣＲＦ血清脂质、Ｌｐ、Ａｐｏ含量的影响无显著意义（Ｐ＞０．０５）。更多还原

【Abstract】 evels of lipid , lipoprotein (Lp) and apolipopro-tein (Apo) in serum were measured in 27 patients withnephrotic syndrome (NS) . 34 patients with chronic re-nal failure (CRF) and 100 healthy control subjects.The results showed : 1) There were abnormal changesin lipid (TC. TG) . .Lp (HDLc. HDL2c . HDL3c ) andApoA1, ApoB100, ApoE) in patients with NS( P < 0. 02or 0. 001) and CRF (P< 0. 01 or 0. 001). 2) Comnaredwith non-dialyzed, reduction of lipid. Lp Apo in HDpatients were not significant (P>0. 05). 3)Determina-tion of serurn ApoE was sensitive and reliable withdouble monoclonal antibodies sandwich enzyme linkedimmunosorbent assay offered by our school.更多还原