【摘要】 在兔脑低氧模型上，以大脑皮层体感诱发电位ＳＥＰ为指标，按Ｌ９（３）４正交设计．随机对照研究ＶＩＳＡ高效剂抗低氧／复氧脑损害的作用。结果表明，ＶＩＳＡ高效剂不仅能增进常氧时大脑皮质电兴奋，而且低氧早期静注ＶＩＳＡ高效剂，低氧／复氧损害后，ＳＥＰ提前恢复，Ｐ２潜伏期，Ｎ１Ｐ２峰峰值显著大于对照值（Ｐ<０． ０１）。结论：ＶＩＳＡ高效剂具有防御低氧／复氧脑损害的作用，可供临床脑复苏借鉴。更多还原

【Abstract】 According to the orthogonal design of L9 (3)4, the effects of VISA agent on defending hypoxic cerebral damage were randomly assessed by the parameters of cerebral conical somatosensory evoked potential (SEP) in the intact hypoxic rabbit model in comparison with the control. The results suggested that administration of VISA agent in normoxia and early hyporia not only improves cerebral cortical electric excitation but also promotes significantly the earlier recovery of standard SEP waves, the marked increase in latency of P2 waves and N1P2 wave amplitude as compared with the control (P < 0. 01 ). It is concluded that the therapeutic potential of VISA agent presented is probably useful in clinical cerebral resuscitation.更多还原