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膀胱移行细胞癌分级诊断的研究中三种定量分析方法的评价
Evaluation of 3 quantitative analysing methods used in grading of urinary bladder carcinoma
【摘要】 应用HI-CI真彩色病理图像分析仪对86例移行细胞癌的核形态,DNA量和AgNoRs颗粒进行了定量分析。三种方法分别和综合作分级判别分析。分级结果与WHO分级结果对比并分析他们与预后的关系。结果证明,三种定量方法在膀胱癌分级诊断中都是比较客观而有价值的方法。1级癌的判别效果最好,一致率为90.9%~100%。各种方法分级与WHO一致率以形态定量法较好,为86.0%,AgNoRs为77.9%,DNA为76.7%。对预后估计的价值以AgNoRs法最好,DNA法次之。三种方法综合分级判别可稍提高分级诊断一致率,达88.4%。
【Abstract】 Nucleal morphometric , DNA and AgNoRs quantification in 86 cases of urinary bladder carcinoma were analysed by computer-assisted image analysing system. The histopathological grading was compared with WHO classification. The result verified that all the 3 quantitative analyses are objective and valuable in grading of the bladder carcinoma, being the best for G1 tumors(90. 9%~100%). AgNoRs is the best for prognosis, DNA being the next. Grading with the synergic analysis of the 3 methods raised the coincidence to 88.4%.
- 【文献出处】 中华泌尿外科杂志 ,CHINESE JOURNAL OF VROLOGY , 编辑部邮箱 ,1994年06期
- 【分类号】R737.14
- 【被引频次】4
- 【下载频次】36