【摘要】 对１２例正常人、４８例冠心病患者进行了９９ｍＴｃ－ＭＩＢＩ平面门控心肌显像，探讨了三种计算左室心肌收缩分数（ＬＶＣＦ）的方法，并与心血池显像的左室射血分数（ＬＶＥＦ）做了相关分析，结果表明：计数法计算ＬＶＣＦ重复性最好，面积法次之，轴缩短法最差；三者与ＬＶＥＦ的相关关系依上顺序递减．相关系数分别为０．８６、０．７３和０．６２．同时研究了ＬＶＣＦ与心肌断层显像（ＳＰＥＣＴ）测定的心肌梗塞范围分数（ＤＦ）的相关性，计数法ＬＶＣＦ与ＤＦ间具有明显负相关（ｒ＝－０．８９），并能通过回归公式预测．结果表明：平面门控心肌显像能较客观地评价左心功能及心肌病变范围，弥补普通平面显像的不足，值得进一步探讨与应用．更多还原

【Abstract】 Abstract In this paper, we proposed and analysed three methods of calculating LVCF from 99mTc-MIBI studies. 12 normal subjects and 48 patients with coronary heart disease (CHD) underwent 99mTc-MIBI myocardial imaging, including tomography (SPECT) and planar gated scintigraphy, and radionuclide ventriculography (RNV). All data were correlated to LVEF and myocardial defect size (DF) measured by SPECT. The results showed that the reproducibility of count mode which was based on the end systolic increase in myocardial count density to calculate LVCF was best of all three methods. The corresponding correlation coefficients (r), standard errors (Sx) and the regression line were as follows (in %): LVCF=0.54 × EF+24.21; r=0.86; Sx=4.84. LVCF=-0.62 × DF+65.3; r=-0.89, Sx= 5.38. In conclusion, estimaton of the left ventricular function and infarct size by the bove defined CF is feasible,easy to perform and clinically meaningful. 99mTc-MIBI gated myocardial imaging can provide data on myocardial perfusion and function, combining both aspects of nuclear cardiology in one procedure.更多还原