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甲状旁腺显像定位诊断原发性甲状旁腺机能亢进
LOCALIZATION OF PRIMARY HYPERPARATHYROIDISM WITH PARATHYROTD IMAGING
【摘要】 应用甲状旁腺显像,并经手术及病理确诊17例原发性甲状旁腺机能亢进患者.我们采用了201TI和99mTC-MIBI互两种甲状旁腺显像剂及201T1/99mTcO4-、99mTc-MIBI/99mTcO4-减影法和99Tc-MIBI双时相法三种显像方法.17例的病理结果为15例甲状旁腺癌(1例为多发,2个腺瘤),1例癌及1例增生.甲状旁腺显像准确定位17个腺体,1例假阴性.此例系位于上纵隔主动脉前方的异位甲状旁腺瘤,显像时视野未包括上胸部而漏诊.定位准确率为94.1%(按腺体数计为94.4%).17例中15例术前也进行了B超检查,3个腺瘤未发现,定位准确率为86.7%(81.3%).由于倒数有限,无法比较三种显像方法的准确率,但99mTC-MIBI双时相法无论对于病人或操作者均最简单易行.
【Abstract】 Abstract cases of primary hyperparathyroidism wre studied by parathyroid imaging and confirmed surgically and pathologically.Two parathyroid imaging agents,201TI and 99mTc-MIBI,and three methods,201TI/99mTc pertechnetate,99mTc-MIBI/99mTc pertechnetate subtraction imaging and 99mTc-MIBI double-phase study were used. Among the 17 cases,the pathological results showed 16 parathyroid adenomas(1 case with 2 adenomas),1 carcinoma and 1 hyperplastic gland.The parathyroid imaging correctly predicted the sites of 17 glands and missed one.In the latter case,the adenoma located in the upper mediastinum just in front of the aorta,but during the imaging process,the upper portion of the thorax had not been included in the field of view.The overall detection rate was 94.1% (94.4%).15 of 17 cases were also studied by ultrasonography.Three adenomas were missed, the detection rate being 56.7%(81 .3%).Due to the limited number of cases,it is difficult to make comparison between different methods.However,the 99mTc-MIBI double-phase study seems to be most easy to perform both for the patients and for the operators.
- 【文献出处】 中华核医学杂志 ,CHINESE JOURNAL OF NUCLEAR MDEICINE , 编辑部邮箱 ,1994年01期
- 【分类号】R817.46
- 【被引频次】20
- 【下载频次】88