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肢端肥大症的放射治疗
RADIOTHERAPY OF ACROMEGALY
【摘要】 报告363例肢端肥大症的治疗结果。单纯放疗205例,手术加放疗158例。以治疗前后血浆生长激素变化为疗效判定标准,单纯放疗和手术加放疗的3、5年完全缓解率分别为24.1%、47.0%和29.7%、54.8%。疗效与剂量有关。复发率为9.1%,45Gy以下发发率高。垂体前叶功能低下是最常见的并发症。放疗后生长激素下降缓慢,仍可对组织和器官起作用。
【Abstract】 AbstractFrom 1954 to 1989, 363 patients with acromegaly were treated by radiotherapy. Of these,205 received radiotherapy alone and 158 , postoperative radiotherapy。 Treatment result was eval-uated on the basis of growth hormone, Complete remission rates of 3-years and 5一years in ra-diotherapy alone group were 24.1%, 47.0%and 29.7%, 54.8%in postoperative radiotherapygroup, respctively。 The results of treatment were related to radiation dose. The recurrence ratewas 9.1%, Hypopituitarism is one of the most common complications. Because of slow decreaseof growth hormone after radiothrapy,it still effects the tissues and organs before growth hormonereturn up to normal level.
- 【文献出处】 中华放射肿瘤学杂志 ,CHINESE JOURNAL OF RADIATION ONCOLOGY , 编辑部邮箱 ,1994年04期
- 【分类号】R584.11
- 【被引频次】3
- 【下载频次】40