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周围神经粘合与缝合的比较研究
Tissue Adhesive Versus Suture in Peripberal Nerve :A Comparative Study
【摘要】 报告用三种不同的粘合剂吻接周围神经的修复效果,并与缝合法进行了比较。将60只大白鼠随机分为4组,每组15只。切断左侧坐骨神经。I组用纤维蛋白粘合剂吻接神经,Ⅱ组用酶粘合剂粘接神经,Ⅲ组用ZT胶行神经外膜对合,K组用9—0缝合针线行常规神经外膜缝合。术后1、2、3月时将每组动物各取5只检测。动态观测诱发肌电图、光镜及电镜下超微结构的变化以评价其修复效果。结果表明,粘合法是一种修复周围神经损伤的有效方法,效果与缝合法无明显差异,并且具有省时、无神经损伤、异物反应轻微、神经吻接准确等突出优点。
【Abstract】 Sixty rats were divided into four groups. Each left sciatic nerve was transected.In the first group.the anastomoses was per-formed on the sevred ends with fibrin glue. In the second group,the cut ends were joined with enzyme adhesive. In the third group,ZT glue was used to connect the ends. In the fourth group,the nerve was repaired by a epineural suture of 9-0 nylon. Five animalsfrom each group were reexplord in 1,2 and 3 months postoperatively. The assesment of the four methods was based on electrophysi-ologic measurement, histologic findings and observation of ultrastructure. The result showed that tissue adhesive was effective inperipheral nerve repair. It has prominent advantages of simplicity and causes no trauma to the nerve ends or slight tissue reaction atJunction site.
- 【文献出处】 中华创伤杂志 ,CHINESE JOURNAL OF TRAUMATOLOGY , 编辑部邮箱 ,1994年06期
- 【分类号】R651.3
- 【被引频次】1
- 【下载频次】48