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浙江省耐甲氧西林金黄色葡萄球菌流行状况及耐药性

STUDY ON THE EPIDEMIOLOGY AND DRUG RESISTANCE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS(MRSA)IN ZHEJIANG PROVINCE

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【作者】 俞云松干梦九马亦林魏泽庆傅素珍

【Author】 Yu Yun-song,Gan Meng-jiu,Ma Yi-lin,et al. Department of Infectious Diseases,The First Affiliated Hospital,Zhejiang Medical Un1versity,Hangzhou,310003

【机构】 浙江医科大学附属一院

【摘要】 对我省各地区1991年6月至1992年12月间收集的170株临床分离的金黄色葡萄球菌的研究表明:在我省同样存在耐甲氧西林金黄色葡萄球菌(MRSA)的流行,在170株菌株中共检出了MRSA44株,占同期金黄色葡萄球菌的25.9%,且在大多数地区都检测到了MRSA菌株;对其耐药性进行研究发现,MRSA菌株对大多数抗生素的耐药率都比较高,对有的抗生素的耐药率在90%以上,耐药程度明显高于甲氧西林敏感的金黄色葡萄球菌(MSSA),但对万古霉素全部敏感。

【Abstract】 e studied 170 strains of staphylococcus aureus isolated from various kinds of clinical specimens collected from different districts of Zhejiang province‘from june 1991 to december 1992. The result showed that methicillin-resistant staphylococcus aureus(MRSA)is also epidemic in our province.as other districts reported.We isolated out 44 strains of MRSA out of the 170 strains isolated,the isolation rate was 25.9%. MRSA strain was isolated from most of the areas in our province. Drug susceptibility test of the 44 MRSA strains revealed that the antibiotic resistance rate were more than 50% to fluoroquinolones,aminoglycosides and most of the cephalosporins-To some of the antibiotics the drug resistant rate was more than 90%, it was obviously higher than methicillin-sensitive staphylococcus aureus(MSSA).However,all the staphylococcus aureus strains(including MRSA and MSSA)were sensitive to vancomycin.

【基金】 浙江省教育委员会资助
  • 【文献出处】 中华传染病杂志 ,CHINESE JOURNAL OF INFECTIOUS DISEASES , 编辑部邮箱 ,1994年03期
  • 【分类号】R378.11
  • 【被引频次】20
  • 【下载频次】70
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