【摘要】 研究60例胃癌血清甲状腺激素水平的变化.所有患者中出现低T₃占57%,低T₄占17%.早期胃癌血清T₃、T₄均无变化,进展期胃病以血清T₃降低为主,其降低程度与肿瘤浸润深度、淋巴结受累、远处转移相一致,晚期胃癌、病情危重者血清T₄降低.表明这种变化能较好地反映胃癌生物学特性,可作为判断病情及临床分期、监视病情、预报复发转移的参考指标.更多还原

【Abstract】 The changes of serum triiodothyronine(T3)and thyroxine(T4)in patients with gastric cancer were studied. 57% of 60 patients had low serurn T3 and 17% had low serum T4. Serum thyroid hormones were normal in early gastric cancer,but serum T3 levels were significantly decreased in patients with advanced cancer. The degree of decrease in serum T3 was related with the depth of infiltration.extent of lym-phonode metastasis and distant metastasis. Low serum T4 heralded a grave prognosis. During the phase of recovery .their serum T3 and T4 returned to normal range in most of the patients. It is considered that low serum concentration of T3 or T4,or both in patients with gastric cancer may be clinically significant,which may reflect biological behavior .stage of the disease, prognosis and may be helpful in predicting recurrence or metastasis of the tumor.更多还原