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经导管肝动脉化疗及栓塞术治疗不能切除的原发性肝癌(附70例报告)

Transcatheter Hepatic Artery Chemotherapy and Embolization in the Treatment of 70 Unresectable Primary Liver Cancer

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【作者】 程广源许戈良徐荣楠李国琪周诗安

【Author】 Cheng Guang-Yuan et al Department of Oncology,Provincial Hospital of Anhui,Hefei

【机构】 安徽省立医院安徽省立医院 安徽省合肥市230001 肿瘤科安徽省合肥市230001 外科安徽省合肥市230001 放射科安徽省合肥市230001 放射科

【摘要】 1988年6月~1992年1月经导管肝动脉灌注化疗及栓塞术治疗不能切除的原发性肝癌70例,男64例,女6例.年龄23岁~66岁,中位年龄47.6岁.Ⅱ期57例,Ⅲ期13例.采用Seldinger氏插管法.治疗方式分3种:TAI、LP—TAE及LP+GS-TAE.经治疗80%病人临床症状改善,疼痛减轻或消失,肿瘤缩小.67.6%病人AFP降低或转阴.生存期延长,半年、1年、2年及3年总生存率分别为62.1%(41/66)、42%(21/50)、34.6%(9/26)及31.6%(6/19).研究表明LP十GS-TAE对不能手术切除的肝癌患者应作为首选疗法.

【Abstract】 Seventy patients with unresectablc primary liver cancer were treated with transcatheter hepatic artery infusion and embolization during the period from June 1988 to January 1992. 64 patients were males and 6 females and aged 23-66 years(mean47. 6 years). Fifty-seven cases of this series were of stage Ⅱ disease and 13 stage Ⅲ. Seldinger needle was used to insert the catheter in the femoral artery. In 80% of the patients symptoms and pains were ameliorated and tumor size reduced after treatment. In 67. 6% of cases,AFP values were either declined or turned negative. The duration of survival were prolonged and the survivals for 6 months and 1, 2and3years rated 62. 1% (41/66), 42% (21/50), 34. 6%(9/26), 31. 6%(6/19)respectively. The findings demonstrated that TAE with lipoidol and jelly foam plus chemotherapeutic agent is a good choice for palliative treatment in patients with unresectable hepatic carcinoma.

  • 【文献出处】 中国肿瘤临床 ,Chinese Journal of Clinical Oncology , 编辑部邮箱 ,1994年03期
  • 【分类号】R735.7
  • 【被引频次】14
  • 【下载频次】22
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