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高效液相色谱法测定糖浆剂中扑尔敏与伪麻黄碱的含量

Determination of the Concentration of Chlorphenamine and Pseudoepherine in Syrup by HPLC

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【作者】 张晔毛磊于文力胡昌

【Author】 Zhang Ye; Mao Lei; Yu Wenli, Hu Chang (The National Institutes of Pharmaceutical Research and Development, Beijing 102206)

【机构】 中国医药研究开发中心

【摘要】 采用高效液相色谱法测定了抗感冒糖浆剂中扑尔敏与伪麻黄碱的含量。方法以扑热息痛做内标,扑尔敏的回收率为99.43%(n=5),伪麻黄碱的回收率为99.64%(n=5)。

【Abstract】 A sensitive and simplified high ferformance liquid chromatographic proced ure has been developed to determine chlorphenamine and pse udoepherine in syr up used for the treatment of cold. The recoveries are 99. 43%and 9 9.64%。 Paracetamol was used as internal standard and the detector wavelength was 210 nm. The method can also be used in the determination of the concentration of chlorphenamine and pseudoepherine of other complex formulations.

  • 【文献出处】 中国药科大学学报 ,JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY , 编辑部邮箱 ,1994年01期
  • 【分类号】R914.1
  • 【被引频次】7
  • 【下载频次】88
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