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马立克氏病二价疫苗稳定性的研究

Studies on the stability of bivalent vaccine of Marek’s disease

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【作者】 甘军纪张如宽彭大新刘金彪吴长新刘秀梵

【Author】 Gan Junji; Zhang Rukuan; Peng DaxinLiu Jinbiao; Wu Changxin; Liu Xiufan(Department of Animal Scienece and Veterinary Medicine,Jang Su Agricultural College)

【机构】 江苏农学院畜禽传染病实验室

【摘要】 马立克氏病二价疫苗(Z4+Fc-126)是一种需在液氮中保存的细胞结合性疫苗.试验表明,疫苗在液氮中保存一年对效价没有影响.疫苗从液氮中取出后,用37℃温水融化对疫苗病毒的损失最小.根据疫苗在18种稀释液中的稳定性试验结果,选出一种(5%肉汤-SPG)作为疫苗的指定稀释液.用该稀释液稀释的疫苗在使用过程中,存放在冰浴上(0℃)能最好地维持疫苗的稳定性.

【Abstract】 The bivalent vaccine of Marek’s disease is a cell associated vaccine which have to be preserved in liquid nitrogen.The valent of the vaccine preserved in liquid nitrogen for one year is not affected by lower temperature.37℃ water bath was the but way to to the tham the vaccine.According stability of vaccine preserved in 18 kinds of different dilution,the 5% Broth-SPG was the best dilution and was recommended.Vaccine diluted by Broth-SPG can be kept in ice-water bath to maintain a good stability.

  • 【分类号】S852.5
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